8QQ1

SpNOX dehydrogenase domain, mutant F397W in complex with Flavin adenine dinucleotide (FAD)

8QQ1 の概要

• エントリーDOI: 10.2210/pdb8qq1/pdb
• 分子名称: Oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, BROMIDE ION, ... (4 entities in total)
• 機能のキーワード: streptococcus pneumoniae nadph oxidase (spnox) reactive oxygen species (ros) membrane protein electron transfer oxidative stress, membrane protein
• 由来する生物種: Streptococcus pneumoniae
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 81363.62

構造登録者

Humm, A.S.,Dupeux, F.,Vermot, A.,Petit-Harleim, I.,Fieschi, F.,Marquez, J.A. (登録日: 2023-10-03, 公開日: 2024-05-08)

• 主引用文献: Petit-Hartlein, I.,Vermot, A.,Thepaut, M.,Humm, A.S.,Dupeux, F.,Dupuy, J.,Chaptal, V.,Marquez, J.A.,Smith, S.M.E.,Fieschi, F.; X-ray structure and enzymatic study of a bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX.; Elife, 13:-, 2024; PubMed: 38640072; DOI: 10.7554/eLife.93759

実験手法

X-RAY DIFFRACTION (1.941 Å)