8QMX

OPR3 wildtype in complex with NADPH4

Summary for 8QMX

• Entry DOI: 10.2210/pdb8qmx/pdb
• Descriptor: 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE, [[(2R,3S,4R,5R)-5-(5-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, ... (5 entities in total)
• Functional Keywords: old yellow enzyme, ene-reductase, flavoenzyme, nadph, flavoprotein
• Biological source: Solanum lycopersicum (tomato)
• Total number of polymer chains: 2
• Total formula weight: 92079.55

Authors

Bijelic, A.,Macheroux, P.,Kerschbaumer, B. (deposition date: 2023-09-25, release date: 2024-01-17, Last modification date: 2024-04-10)

• Primary citation: Kerschbaumer, B.,Totaro, M.G.,Friess, M.,Breinbauer, R.,Bijelic, A.,Macheroux, P.; Loop 6 and the beta-hairpin flap are structural hotspots that determine cofactor specificity in the FMN-dependent family of ene-reductases.; Febs J., 291:1560-1574, 2024; PubMed: 38263933; DOI: 10.1111/febs.17055

Experimental method

X-RAY DIFFRACTION (1.4 Å)