8QIY
Structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with inhibitor
Summary for 8QIY
Entry DOI | 10.2210/pdb8qiy/pdb |
Descriptor | Phosphopantetheine adenylyltransferase, 1-(2-aminophenyl)-5-(trifluoromethyl)pyrazole-4-carboxylic acid (3 entities in total) |
Functional Keywords | coad, ppat, nucleotidyltransferase, transferase |
Biological source | Mycobacteroides abscessus |
Total number of polymer chains | 3 |
Total formula weight | 52973.05 |
Authors | Thomas, S.E.,McCarthy, W.J.,Coyne, A.G.,Blundell, T.L. (deposition date: 2023-09-12, release date: 2024-07-24, Last modification date: 2024-09-11) |
Primary citation | McCarthy, W.J.,Thomas, S.E.,Olaleye, T.,Boland, J.A.,Floto, R.A.,Williams, G.,Blundell, T.L.,Coyne, A.G.,Abell, C. A Fragment-Based Competitive 19 F LB-NMR Platform For Hotspot-Directed Ligand Profiling. Angew.Chem.Int.Ed.Engl., 63:e202406846-e202406846, 2024 Cited by PubMed: 38896426DOI: 10.1002/anie.202406846 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5149 Å) |
Structure validation
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