8QIX

Structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with inhibitor

8QIX の概要

• エントリーDOI: 10.2210/pdb8qix/pdb
• 分子名称: Phosphopantetheine adenylyltransferase, 3-(3-methylindol-1-yl)-~{N}-(4-phenoxyphenyl)sulfonyl-propanamide (3 entities in total)
• 機能のキーワード: coad, ppat, nucleotidyltransferase, transferase
• 由来する生物種: Mycobacteroides abscessus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 53299.67

構造登録者

Thomas, S.E.,McCarthy, W.J.,Coyne, A.G.,Blundell, T.L. (登録日: 2023-09-12, 公開日: 2024-07-24)

• 主引用文献: McCarthy, W.J.,Thomas, S.E.,Olaleye, T.,Boland, J.A.,Floto, R.A.,Williams, G.,Blundell, T.L.,Coyne, A.G.,Abell, C.; A fragment based competitive 19F LB-NMR platform for hotspot directed ligand profiling.; Angew.Chem.Int.Ed.Engl., :e202406846-e202406846, 2024; PubMed: 38896426; DOI: 10.1002/anie.202406846

実験手法

X-RAY DIFFRACTION (1.579 Å)