8QAB

X-ray crystal structure of a de novo designed antiparallel coiled-coil hexameric alpha-helical barrel with 4 heptad repeats, apCCHex

Summary for 8QAB

Entry DOI	10.2210/pdb8qab/pdb
Descriptor	apCCHex, 1-methoxy-2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethane (3 entities in total)
Functional Keywords	coiled coil, alpha-helical barrel, de novo protein design, peptide assembly, de novo protein
Biological source	synthetic construct
Total number of polymer chains	6
Total formula weight	20949.80
Authors	Naudin, E.N.,Albanese, K.I.,Petrenas, R.,Woolfson, D.N. (deposition date: 2023-08-22, release date: 2024-07-03)
Primary citation	Albanese, K.I.,Petrenas, R.,Pirro, F.,Naudin, E.A.,Borucu, U.,Dawson, W.M.,Scott, D.A.,Leggett, G.J.,Weiner, O.D.,Oliver, T.A.A.,Woolfson, D.N. Rationally seeded computational protein design of ɑ-helical barrels. Nat.Chem.Biol., 2024 Cited by PubMed: 38902458 DOI: 10.1038/s41589-024-01642-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation