8Q7L
Tau - AD-MIA6 (tau intermediate amyloid)
Summary for 8Q7L
Entry DOI | 10.2210/pdb8q7l/pdb |
EMDB information | 18219 |
Descriptor | Isoform Tau-D of Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | amyloid, tau, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 240016.64 |
Authors | Lovestam, S.,Li, D.,Scheres, S.H.W.,Goedert, M. (deposition date: 2023-08-16, release date: 2023-08-30, Last modification date: 2024-01-24) |
Primary citation | Lovestam, S.,Li, D.,Wagstaff, J.L.,Kotecha, A.,Kimanius, D.,McLaughlin, S.H.,Murzin, A.G.,Freund, S.M.V.,Goedert, M.,Scheres, S.H.W. Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625:119-125, 2024 Cited by PubMed: 38030728DOI: 10.1038/s41586-023-06788-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.82 Å) |
Structure validation
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