8Q56

PglX methyltransferase of Salmonella BREX phage defence system (aka BrxX) bound to inhibitor Ocr

Summary for 8Q56

Entry DOI	10.2210/pdb8q56/pdb
Descriptor	site-specific DNA-methyltransferase (adenine-specific), Protein Ocr, S-ADENOSYLMETHIONINE, ... (4 entities in total)
Functional Keywords	methyltransferase, phage defense, dna binding, dna binding protein
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium str. D23580 More
Total number of polymer chains	2
Total formula weight	155724.81
Authors	Went, S.C.,Blower, T.R. (deposition date: 2023-08-08, release date: 2024-08-21, Last modification date: 2024-09-04)
Primary citation	Went, S.C.,Picton, D.M.,Morgan, R.D.,Nelson, A.,Brady, A.,Mariano, G.,Dryden, D.T.F.,Smith, D.L.,Wenner, N.,Hinton, J.C.D.,Blower, T.R. Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence. Nat Commun, 15:7236-7236, 2024 Cited by PubMed: 39174540 DOI: 10.1038/s41467-024-51629-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation