8Q3W
ATP-bound IstB in complex to duplex DNA
Summary for 8Q3W
Entry DOI | 10.2210/pdb8q3w/pdb |
EMDB information | 18136 3031 3032 |
Descriptor | Insertion sequence IS5376 putative ATP-binding protein, DNA (48-MER) Target DNA FW, DNA (48-MER) Traget DNA Rv, ... (5 entities in total) |
Functional Keywords | dna transposition, transposon, transpososome, aaa+ atpases, target dna, is21, istb, insertion sequence, dna binding protein, cryo-electron microscopy. |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 12 |
Total formula weight | 338324.27 |
Authors | de la Gandara, A.,Spinola-Amilibia, M.,Araujo-Bazan, L.,Nunez-Ramirez, R.,Berger, J.M.,Arias-Palomo, E. (deposition date: 2023-08-04, release date: 2024-07-10) |
Primary citation | de la Gandara, A.,Spinola-Amilibia, M.,Araujo-Bazan, L.,Nunez-Ramirez, R.,Berger, J.M.,Arias-Palomo, E. Molecular basis for transposase activation by a dedicated AAA+ ATPase. Nature, 630:1003-1011, 2024 Cited by PubMed: 38926614DOI: 10.1038/s41586-024-07550-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.18 Å) |
Structure validation
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