8Q1R
mouse Keap1 in complex with stapled peptide
Summary for 8Q1R
Entry DOI | 10.2210/pdb8q1r/pdb |
Descriptor | Kelch-like ECH-associated protein 1, Stapled peptide, SULFATE ION, ... (6 entities in total) |
Functional Keywords | keap1, cyclic peptide, e3 ligase adaptor, antioxidant response, ligase |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 34665.72 |
Authors | |
Primary citation | Iegre, J.,Krajcovicova, S.,Gunnarsson, A.,Wissler, L.,Kack, H.,Luchniak, A.,Tangefjord, S.,Narjes, F.,Spring, D.R. A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction. Chem Sci, 14:10800-10805, 2023 Cited by PubMed: 37829032DOI: 10.1039/d3sc04083f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.33 Å) |
Structure validation
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