8Q1Q

mouse Keap1 in complex with stapled peptide

Summary for 8Q1Q

• Entry DOI: 10.2210/pdb8q1q/pdb
• Descriptor: Kelch-like ECH-associated protein 1, Stapled peptide, SULFATE ION, ... (5 entities in total)
• Functional Keywords: keap1, cyclic peptide, e3 ligase adaptor, antioxidant response, ligase
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 34997.17

Authors

Kack, H.,Wissler, L. (deposition date: 2023-08-01, release date: 2023-10-25)

• Primary citation: Iegre, J.,Krajcovicova, S.,Gunnarsson, A.,Wissler, L.,Kack, H.,Luchniak, A.,Tangefjord, S.,Narjes, F.,Spring, D.R.; A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction.; Chem Sci, 14:10800-10805, 2023; PubMed: 37829032; DOI: 10.1039/d3sc04083f

Experimental method

X-RAY DIFFRACTION (1.378 Å)