8Q1M

Aplysia californica acetylcholine-binding protein in complex with Spiroimine (+)-4 R

8Q1M の概要

• エントリーDOI: 10.2210/pdb8q1m/pdb
• 分子名称: Soluble acetylcholine receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spiroimine (+)-4 R, ... (6 entities in total)
• 機能のキーワード: achbp, complex, spiroimine, aplysia californica, choline-binding protein
• 由来する生物種: Aplysia californica (California sea hare)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 125901.13

構造登録者

Sulzenbacher, G.,Bourne, Y.,Marchot, P. (登録日: 2023-07-31, 公開日: 2024-04-03, 最終更新日: 2024-05-08)

• 主引用文献: Bourne, Y.,Sulzenbacher, G.,Chabaud, L.,Araoz, R.,Radic, Z.,Conrod, S.,Taylor, P.,Guillou, C.,Molgo, J.,Marchot, P.; The Cyclic Imine Core Common to the Marine Macrocyclic Toxins Is Sufficient to Dictate Nicotinic Acetylcholine Receptor Antagonism.; Mar Drugs, 22:-, 2024; PubMed: 38667766; DOI: 10.3390/md22040149

実験手法

X-RAY DIFFRACTION (2 Å)