8PTX

Cryo-EM structure of human Elp123 in complex with tRNA, acetyl-CoA, 5'-deoxyadenosine and methionine

Summary for 8PTX

• Entry DOI: 10.2210/pdb8ptx/pdb
• EMDB information: 17924
• Descriptor: Elongator complex protein 1, Elongator complex protein 2, Elongator complex protein 3, ... (9 entities in total)
• Functional Keywords: elongator, trna modification, acetyl-coa hydrolysis, translation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 484899.39

Authors

Abbassi, N.,Jaciuk, M.,Lin, T.-Y.,Glatt, S. (deposition date: 2023-07-16, release date: 2024-04-17, Last modification date: 2024-05-22)

• Primary citation: Abbassi, N.E.,Jaciuk, M.,Scherf, D.,Bohnert, P.,Rau, A.,Hammermeister, A.,Rawski, M.,Indyka, P.,Wazny, G.,Chramiec-Glabik, A.,Dobosz, D.,Skupien-Rabian, B.,Jankowska, U.,Rappsilber, J.,Schaffrath, R.,Lin, T.Y.,Glatt, S.; Cryo-EM structures of the human Elongator complex at work.; Nat Commun, 15:4094-4094, 2024; PubMed: 38750017; DOI: 10.1038/s41467-024-48251-y

Experimental method

ELECTRON MICROSCOPY (2.87 Å)