8PRV

Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosreductase domain (FASamn sample)

Summary for 8PRV

• Entry DOI: 10.2210/pdb8prv/pdb
• EMDB information: 17839
• Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
• Functional Keywords: fatty acid synthase, acyl carrier protein, fas, acp, cytosolic protein
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 3
• Total formula weight: 646548.36

Authors

Singh, K.,Bunzel, G.,Graf, B.,Yip, K.M.,Stark, H.,Chari, A. (deposition date: 2023-07-12, release date: 2023-11-22)

• Primary citation: Singh, K.,Bunzel, G.,Graf, B.,Yip, K.M.,Neumann-Schaal, M.,Stark, H.,Chari, A.; Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.; Cell, 186:5054-5067.e16, 2023; PubMed: 37949058; DOI: 10.1016/j.cell.2023.10.009

Experimental method

ELECTRON MICROSCOPY (2.9 Å)