8POI
Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine
Summary for 8POI
| Entry DOI | 10.2210/pdb8poi/pdb |
| NMR Information | BMRB: 34831 |
| Descriptor | Survival of motor neuron-related-splicing factor 30, 4-pyridin-2-yl-1,3-thiazol-2-amine (2 entities in total) |
| Functional Keywords | tudor domain, complex, inhibitor, rna binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 7112.74 |
| Authors | Borggraefe, J.,Gaussmann, S.,Sattler, M. (deposition date: 2023-07-04, release date: 2023-08-23, Last modification date: 2023-08-30) |
| Primary citation | Enders, L.,Siklos, M.,Borggrafe, J.,Gaussmann, S.,Koren, A.,Malik, M.,Tomek, T.,Schuster, M.,Reinis, J.,Hahn, E.,Rukavina, A.,Reicher, A.,Casteels, T.,Bock, C.,Winter, G.E.,Hannich, J.T.,Sattler, M.,Kubicek, S. Pharmacological perturbation of the phase-separating protein SMNDC1. Nat Commun, 14:4504-4504, 2023 Cited by PubMed: 37587144DOI: 10.1038/s41467-023-40124-0 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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