8PMJ

Vanadate-trapped BSEP in nanodiscs

Summary for 8PMJ

Entry DOI	10.2210/pdb8pmj/pdb
EMDB information	17761
Descriptor	Bile salt export pump, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... (7 entities in total)
Functional Keywords	transport, nucleotide, vanadate, nanodiscs, protein transport
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	149201.94
Authors	Liu, H.,Irobalieva, R.N.,Kowal, J.,Ni, D.,Nosol, K.,Bang-Sorensen, R.,Lancien, L.,Stahlberg, H.,Stieger, B.,Locher, K.P. (deposition date: 2023-06-28, release date: 2023-11-29)
Primary citation	Liu, H.,Irobalieva, R.N.,Kowal, J.,Ni, D.,Nosol, K.,Bang-Sorensen, R.,Lancien, L.,Stahlberg, H.,Stieger, B.,Locher, K.P. Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP. Nat Commun, 14:7296-7296, 2023 Cited by PubMed: 37949847 DOI: 10.1038/s41467-023-43109-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.81 Å)

Structure validation