8PMI

Structure of Nal1 indica cultivar IR64, construct 36-458 in presence of peptide from FZP protein

これはPDB形式変換不可エントリーです。

8PMI の概要

• エントリーDOI: 10.2210/pdb8pmi/pdb
• 分子名称: Protein NARROW LEAF 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: serine protease, plant protein
• 由来する生物種: Oryza sativa Indica Group (long-grained rice)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 281669.44

構造登録者

Huang, L.Y.,Rety, S.,Xi, X.G. (登録日: 2023-06-28, 公開日: 2024-04-17, 最終更新日: 2024-06-05)

主引用文献

Huang, L.Y.,Liu, N.N.,Chen, W.F.,Ai, X.,Li, H.H.,Zhang, Z.L.,Hou, X.M.,Fosse, P.,Mauffret, O.,Lei, D.S.,Rety, S.,Xi, X.G.
The catalytic triad of rice NARROW LEAF1 involves H234.
Nat.Plants, 10:743-748, 2024

PubMed Abstract: NARROW LEAF1 (NAL1) exerts a multifaceted influence on leaf morphology and crop yield. Recent crystal study proposed that histidine 233 (H233) is part of the catalytic triad. Here we report that unlike suggested previously, H234 instead of H233 is a component of the catalytic triad alongside residues D291 and S385 in NAL1. Remarkably, residue 233 unexpectedly plays a pivotal role in regulating NAL1's proteolytic activity. These findings establish a strong foundation for utilizing NAL1 in breeding programs aimed at improving crop yield.

PubMed: 38600265
DOI: 10.1038/s41477-024-01668-1

実験手法

X-RAY DIFFRACTION (2.83 Å)