8PLN

Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 24.

Summary for 8PLN

Entry DOI	10.2210/pdb8pln/pdb
Descriptor	Thioredoxin glutathione reductase, FLAVIN-ADENINE DINUCLEOTIDE, 6,7,8,9-tetrahydro-5~{H}-carbazole-1-carbonitrile, ... (4 entities in total)
Functional Keywords	bi-functional, oxidoreductase, homodimer, flavoprotein
Biological source	Schistosoma mansoni
Total number of polymer chains	1
Total formula weight	65905.72
Authors	Ribeiro, L.,Montoya, B.O.,Moreira-Filho, J.T.,Bowyer, S.,Verma, A.,Neves, B.J.,Owens, R.J.,Andrade, C.H.,Silva-Jr, F.P.,Furnham, N. (deposition date: 2023-06-27, release date: 2024-01-31)
Primary citation	de Souza Neto, L.R.,Montoya, B.O.,Brandao-Neto, J.,Verma, A.,Bowyer, S.,Moreira-Filho, J.T.,Dantas, R.F.,Neves, B.J.,Andrade, C.H.,von Delft, F.,Owens, R.J.,Furnham, N.,Silva-Jr, F.P. Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni. Sci Rep, 14:1582-1582, 2024 Cited by PubMed: 38238498 DOI: 10.1038/s41598-024-52018-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation