8PL2

Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 3.

8PL2 の概要

• エントリーDOI: 10.2210/pdb8pl2/pdb
• 分子名称: Thioredoxin glutathione reductase, FLAVIN-ADENINE DINUCLEOTIDE, ~{N}-(1-propyl-1,2,3,4-tetrazol-5-yl)thiophene-2-carboxamide, ... (4 entities in total)
• 機能のキーワード: bi-functional, oxidoreductase, homodimer, flavoprotein
• 由来する生物種: Schistosoma mansoni
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 131656.22

構造登録者

Ribeiro, L.,Montoya, B.O.,Moreira-Filho, J.T.,Bowyer, S.,Verma, A.,Neves, B.J.,Owens, R.J.,Andrade, C.H.,Silva-Jr, F.P.,Furnham, N. (登録日: 2023-06-27, 公開日: 2024-01-31)

• 主引用文献: de Souza Neto, L.R.,Montoya, B.O.,Brandao-Neto, J.,Verma, A.,Bowyer, S.,Moreira-Filho, J.T.,Dantas, R.F.,Neves, B.J.,Andrade, C.H.,von Delft, F.,Owens, R.J.,Furnham, N.,Silva-Jr, F.P.; Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni.; Sci Rep, 14:1582-1582, 2024; PubMed: 38238498; DOI: 10.1038/s41598-024-52018-2

実験手法

X-RAY DIFFRACTION (1.88 Å)