8PH7

X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DPhF)(O2CCH3)3] in condition A

8PH7 の概要

• エントリーDOI: 10.2210/pdb8ph7/pdb
• 分子名称: Lysozyme C, [Ru2(N,N'-bis(4-fluorophenyl)formamidinate)(1,1-ethanediol), SUCCINIC ACID, ... (6 entities in total)
• 機能のキーワード: ruthenium, protein interaction, metallodrug, diruthenium, hydrolase, protein binding
• 由来する生物種: Gallus gallus (chicken)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15625.29

構造登録者

Teran, A.,Ferraro, G.,Merlino, A. (登録日: 2023-06-19, 公開日: 2023-09-13, 最終更新日: 2023-09-20)

• 主引用文献: Teran, A.,Ferraro, G.,Imbimbo, P.,Sanchez-Pelaez, A.E.,Monti, D.M.,Herrero, S.,Merlino, A.; Steric hindrance and charge influence on the cytotoxic activity and protein binding properties of diruthenium complexes.; Int.J.Biol.Macromol., 253:126666-126666, 2023; PubMed: 37660867; DOI: 10.1016/j.ijbiomac.2023.126666

実験手法

X-RAY DIFFRACTION (1.406 Å)