8PH6

X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(DPhF)(CO3)3] in condition B

8PH6 の概要

• エントリーDOI: 10.2210/pdb8ph6/pdb
• 分子名称: Lysozyme C, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, [Ru2(DPhF)(Formate)(CO3)], ... (7 entities in total)
• 機能のキーワード: ruthenium, protein interaction, metallodrug, diruthenium, hydrolase, protein binding
• 由来する生物種: Gallus gallus (chicken)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16661.15

構造登録者

Teran, A.,Ferraro, G.,Merlino, A. (登録日: 2023-06-19, 公開日: 2023-09-13, 最終更新日: 2023-09-20)

• 主引用文献: Teran, A.,Ferraro, G.,Imbimbo, P.,Sanchez-Pelaez, A.E.,Monti, D.M.,Herrero, S.,Merlino, A.; Steric hindrance and charge influence on the cytotoxic activity and protein binding properties of diruthenium complexes.; Int.J.Biol.Macromol., 253:126666-126666, 2023; PubMed: 37660867; DOI: 10.1016/j.ijbiomac.2023.126666

実験手法

X-RAY DIFFRACTION (1.07 Å)