8PC9

Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 0 ms - native.

8PC9 の概要

• エントリーDOI: 10.2210/pdb8pc9/pdb
• 分子名称: Beta-lactamase, SULFATE ION (3 entities in total)
• 機能のキーワード: catalytic activity, beta-lactamase activity, hydrolase activity, inhibitor, time-resolved, tape drive, hydrolase
• 由来する生物種: Klebsiella pneumoniae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28096.61

構造登録者

Prester, A.,Perbandt, M.,Galchenkova, M.,Oberthuer, D.,Yefanov, O.,Hinrichs, W.,Rohde, H.,Betzel, C. (登録日: 2023-06-11, 公開日: 2024-06-26, 最終更新日: 2024-07-17)

• 主引用文献: Prester, A.,Perbandt, M.,Galchenkova, M.,Oberthuer, D.,Werner, N.,Henkel, A.,Maracke, J.,Yefanov, O.,Hakanpaa, J.,Pompidor, G.,Meyer, J.,Chapman, H.,Aepfelbacher, M.,Hinrichs, W.,Rohde, H.,Betzel, C.; Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.; Commun Chem, 7:152-152, 2024; PubMed: 38969718; DOI: 10.1038/s42004-024-01236-w

実験手法

X-RAY DIFFRACTION (1.4 Å)