8P9W
vitamin D receptor complex with Xe4MeCF3 analog
Summary for 8P9W
Entry DOI | 10.2210/pdb8p9w/pdb |
Descriptor | Vitamin D3 receptor A, Nuclear receptor coactivator 1, (1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-1,7~{a}-dimethyl-1-[6,6,6-tris(fluoranyl)-5-oxidanyl-5-(trifluoromethyl)hexa-1,3-diynyl]-2,3,3~{a},5,6,7-hexahydroinden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, ... (4 entities in total) |
Functional Keywords | nuclear receptor, agonist, ligand binding domain, transcription |
Biological source | Danio rerio (zebrafish) More |
Total number of polymer chains | 2 |
Total formula weight | 36353.26 |
Authors | Belorusova, A.Y.,Rochel, N. (deposition date: 2023-06-06, release date: 2024-06-26, Last modification date: 2024-07-24) |
Primary citation | Len-Tayon, K.,Beraud, C.,Fauveau, C.,Belorusova, A.Y.,Chebaro, Y.,Mourino, A.,Massfelder, T.,Chauchereau, A.,Metzger, D.,Rochel, N.,Laverny, G. A vitamin D-based strategy overcomes chemoresistance in prostate cancer. Br.J.Pharmacol., 2024 Cited by PubMed: 38982588DOI: 10.1111/bph.16492 PDB entries with the same primary citation |
Experimental method |
Structure validation
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