8P8P

Crystal structure of human Histidine Triad Nucleotide-Binding Protein 1 in complex with 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Ethenoadenosine

Summary for 8P8P

• Entry DOI: 10.2210/pdb8p8p/pdb
• Descriptor: Histidine triad nucleotide-binding protein 1, [(2~{R},3~{S},4~{R},5~{R})-5-imidazo[2,1-f]purin-3-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[2-(1~{H}-indol-3-yl)ethyl]carbamate (3 entities in total)
• Functional Keywords: hint, hit, histidine triad, phosphoramidase, complex, inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 28125.34

Authors

Dolot, R.M.,Dillenburg, M.,Wagner, C.R. (deposition date: 2023-06-02, release date: 2023-06-14)

• Primary citation: Dillenburg, M.,Dolot, R.,Wagner, C.R.; Novel inhibitors for hHINT1 protein; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)