8P8P
Crystal structure of human Histidine Triad Nucleotide-Binding Protein 1 in complex with 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Ethenoadenosine
Summary for 8P8P
Entry DOI | 10.2210/pdb8p8p/pdb |
Descriptor | Histidine triad nucleotide-binding protein 1, [(2~{R},3~{S},4~{R},5~{R})-5-imidazo[2,1-f]purin-3-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[2-(1~{H}-indol-3-yl)ethyl]carbamate (3 entities in total) |
Functional Keywords | hint, hit, histidine triad, phosphoramidase, complex, inhibitor, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 28125.34 |
Authors | Dolot, R.M.,Dillenburg, M.,Wagner, C.R. (deposition date: 2023-06-02, release date: 2023-06-14, Last modification date: 2024-06-19) |
Primary citation | Dillenburg, M.,Dolot, R.,Wagner, C.R. Novel inhibitors for hHINT1 protein To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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