8P8P

Crystal structure of human Histidine Triad Nucleotide-Binding Protein 1 in complex with 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Ethenoadenosine

8P8P の概要

• エントリーDOI: 10.2210/pdb8p8p/pdb
• 分子名称: Histidine triad nucleotide-binding protein 1, [(2~{R},3~{S},4~{R},5~{R})-5-imidazo[2,1-f]purin-3-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[2-(1~{H}-indol-3-yl)ethyl]carbamate (3 entities in total)
• 機能のキーワード: hint, hit, histidine triad, phosphoramidase, complex, inhibitor, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28125.34

構造登録者

Dolot, R.M.,Dillenburg, M.,Wagner, C.R. (登録日: 2023-06-02, 公開日: 2023-06-14)

• 主引用文献: Dillenburg, M.,Dolot, R.,Wagner, C.R.; Novel inhibitors for hHINT1 protein; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)