8P6Q
Racemic structure of TNFR1 cysteine-rich domain
Summary for 8P6Q
Entry DOI | 10.2210/pdb8p6q/pdb |
Descriptor | Tumor necrosis factor-binding protein 1, D-TNFR-1 CRD2, SULFATE ION, ... (4 entities in total) |
Functional Keywords | racemic, chemical synthesis, cysteine-rich, cytokine receptor, receptor mimic, cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 11559.65 |
Authors | Lander, A.J.,Jin, Y.,Luk, L.Y.P. (deposition date: 2023-05-28, release date: 2024-01-24, Last modification date: 2024-03-06) |
Primary citation | Lander, A.J.,Kong, Y.,Jin, Y.,Wu, C.,Luk, L.Y.P. Deciphering the Synthetic and Refolding Strategy of a Cysteine-Rich Domain in the Tumor Necrosis Factor Receptor (TNF-R) for Racemic Crystallography Analysis and d-Peptide Ligand Discovery. Acs Bio Med Chem Au, 4:68-76, 2024 Cited by PubMed: 38404743DOI: 10.1021/acsbiomedchemau.3c00060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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