8P6Q

Racemic structure of TNFR1 cysteine-rich domain

8P6Q の概要

• エントリーDOI: 10.2210/pdb8p6q/pdb
• 分子名称: Tumor necrosis factor-binding protein 1, D-TNFR-1 CRD2, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: racemic, chemical synthesis, cysteine-rich, cytokine receptor, receptor mimic, cytokine
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 11559.65

構造登録者

Lander, A.J.,Jin, Y.,Luk, L.Y.P. (登録日: 2023-05-28, 公開日: 2024-01-24, 最終更新日: 2024-03-06)

• 主引用文献: Lander, A.J.,Kong, Y.,Jin, Y.,Wu, C.,Luk, L.Y.P.; Deciphering the Synthetic and Refolding Strategy of a Cysteine-Rich Domain in the Tumor Necrosis Factor Receptor (TNF-R) for Racemic Crystallography Analysis and d-Peptide Ligand Discovery.; Acs Bio Med Chem Au, 4:68-76, 2024; PubMed: 38404743; DOI: 10.1021/acsbiomedchemau.3c00060

実験手法

X-RAY DIFFRACTION (1.4 Å)