8P5G

Kinase domain of wild type human ULK1 in complex with compound CCT241533

Summary for 8P5G

• Entry DOI: 10.2210/pdb8p5g/pdb
• Descriptor: Serine/threonine-protein kinase ULK1, 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: autophagy, unc-like 1 kinase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 65558.66

Authors

Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05)

• Primary citation: Battista, T.,Semrau, M.S.,Lolli, G.,Storici, P.; Crystal structures of ULK1 in complex with KCGS compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.019 Å)