8P42

Full length structure of TcMIP with bound inhibitor NJS227.

8P42 の概要

• エントリーDOI: 10.2210/pdb8p42/pdb
• 分子名称: Macrophage infectivity potentiator, (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• 機能のキーワード: macrophage, potentiator, soluble, protein, structural protein
• 由来する生物種: Trypanosoma cruzi
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37910.83

構造登録者

Whittaker, J.J.,Guskov, A.,Goretzki, B.,Hellmich, U.A. (登録日: 2023-05-19, 公開日: 2024-06-12)

• 主引用文献: Whittaker, J.J.,Guskov, A.,Goretzki, B.,Hellmich, U.A.; Structural dynamics of macrophage infectivity potentiator proteins (MIPs) are differentially modulated by inhibitors and appendage domains; To Be Published,

実験手法

X-RAY DIFFRACTION (2.64 Å)