8P3C

Full length structure of BpMIP with bound inhibitor NJS227.

Summary for 8P3C

• Entry DOI: 10.2210/pdb8p3c/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase, (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: macrophage, potentiator, soluble, protein, structural protein
• Biological source: Burkholderia pseudomallei
• Total number of polymer chains: 1
• Total formula weight: 14469.12

Authors

Whittaker, J.J.,Guskov, A.,Goretzki, B.,Hellmich, U.A. (deposition date: 2023-05-17, release date: 2024-06-12)

• Primary citation: Whittaker, J.J.,Guskov, A.,Goretzki, B.,Hellmich, U.A.; Structural dynamics of macrophage infectivity potentiator proteins (MIPs) are differentially modulated by inhibitors and appendage domains; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.02 Å)