8P2H

Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric state

This is a non-PDB format compatible entry.

Summary for 8P2H

• Entry DOI: 10.2210/pdb8p2h/pdb
• EMDB information: 17365
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... (59 entities in total)
• Functional Keywords: ribosome, fusidic acid, ef-g, antibiotic
• Biological source: Staphylococcus aureus subsp. aureus NCTC 8325; More
• Total number of polymer chains: 53
• Total formula weight: 2251202.88

Authors

Gonzalez-Lopez, A.,Selmer, M. (deposition date: 2023-05-16, release date: 2024-05-01, Last modification date: 2024-07-03)

• Primary citation: Gonzalez-Lopez, A.,Larsson, D.S.D.,Koripella, R.K.,Cain, B.N.,Chavez, M.G.,Hergenrother, P.J.,Sanyal, S.,Selmer, M.; Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.; Sci Rep, 14:14253-14253, 2024; PubMed: 38902339; DOI: 10.1038/s41598-024-64868-x

Experimental method

ELECTRON MICROSCOPY (2.49 Å)