8P11

X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL003044.

8P11 の概要

• エントリーDOI: 10.2210/pdb8p11/pdb
• 分子名称: Acetylcholine-binding protein, CHLORIDE ION, 4-(4-chlorophenyl)piperidin-4-ol, ... (5 entities in total)
• 機能のキーワード: fragment based drug design, acetylcholine-binding protein, choline-binding proteins, choline-binding protein
• 由来する生物種: Lymnaea stagnalis (great pond snail)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 271896.58

構造登録者

Cederfelt, D.,Boronat, P.,Dobritzsch, D.,Hennig, S.,Fitzgerald, E.A.,de Esch, I.J.P.,Danielson, U.H. (登録日: 2023-05-11, 公開日: 2024-05-08)

• 主引用文献: Fitzgerald, E.A.,Cederfelt, D.,Boronat, P.,Aarmo Lund, B.,Dobritzsch, D.,de Esch, I.J.P.,Danielson, U.H.; Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)