8OY4

Time-resolved SFX structure of the class II photolyase complexed with a thymine dimer (300 ps pump-probe delay)

8OY4 の概要

• エントリーDOI: 10.2210/pdb8oy4/pdb
• 分子名称: Deoxyribodipyrimidine photo-lyase, CPD-COMPRISING OLIGONUCLEOTIDE, COUNTERSTRAND-OLIGONUCLEOTIDE, ... (6 entities in total)
• 機能のキーワード: dna binding protein, dna repair enzyme, flavoprotein, photoenzyme, lyase
• 由来する生物種: Methanosarcina mazei Go1; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 132875.81

構造登録者

Lane, T.J.,Christou, N.-E.,Melo, D.V.M.,Apostolopoulou, V.,Pateras, A.,Mashhour, A.R.,Galchenkova, M.,Gunther, S.,Reinke, P.,Kremling, V.,Oberthuer, D.,Henkel, A.,Sprenger, J.,Scheer, T.E.S.,Lange, E.,Yefanov, O.N.,Middendorf, P.,Sellberg, J.A.,Schubert, R.,Fadini, A.,Cirelli, C.,Beale, E.V.,Johnson, P.,Dworkowski, F.,Ozerov, D.,Bertrand, Q.,Wranik, M.,Zitter, E.D.,Turk, D.,Bajt, S.,Chapman, H.,Bacellar, C. (登録日: 2023-05-03, 公開日: 2023-11-22, 最終更新日: 2023-12-13)

• 主引用文献: Christou, N.E.,Apostolopoulou, V.,Melo, D.V.M.,Ruppert, M.,Fadini, A.,Henkel, A.,Sprenger, J.,Oberthuer, D.,Gunther, S.,Pateras, A.,Rahmani Mashhour, A.,Yefanov, O.M.,Galchenkova, M.,Reinke, P.Y.A.,Kremling, V.,Scheer, T.E.S.,Lange, E.R.,Middendorf, P.,Schubert, R.,De Zitter, E.,Lumbao-Conradson, K.,Herrmann, J.,Rahighi, S.,Kunavar, A.,Beale, E.V.,Beale, J.H.,Cirelli, C.,Johnson, P.J.M.,Dworkowski, F.,Ozerov, D.,Bertrand, Q.,Wranik, M.,Bacellar, C.,Bajt, S.,Wakatsuki, S.,Sellberg, J.A.,Huse, N.,Turk, D.,Chapman, H.N.,Lane, T.J.; Time-resolved crystallography captures light-driven DNA repair.; Science, 382:1015-1020, 2023; PubMed: 38033070; DOI: 10.1126/science.adj4270

実験手法

X-RAY DIFFRACTION (2.35 Å)