8OXT

CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) H251A VARIANT COMPLEXED WITH N-ACETYLANTHRANILATE AS RESULT OF IN CRYSTALLO TURNOVER OF ITS NATURAL SUBSTRATE 1-H-3-HYDROXY-4- OXOQUINALDINE UNDER HYPEROXIC CONDITIONS

This is a non-PDB format compatible entry.

Summary for 8OXT

• Entry DOI: 10.2210/pdb8oxt/pdb
• Descriptor: 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-(ACETYLAMINO)BENZOIC ACID, S,R MESO-TARTARIC ACID, ... (6 entities in total)
• Functional Keywords: alpha-beta hydrolase, oxidoreductase, dioxygenase, cofactor-devoid
• Biological source: Paenarthrobacter nitroguajacolicus
• Total number of polymer chains: 2
• Total formula weight: 67743.92

Authors

Bui, S.,Steiner, R.A. (deposition date: 2023-05-02, release date: 2024-01-17)

• Primary citation: Bui, S.,Gil-Guerrero, S.,van der Linden, P.,Carpentier, P.,Ceccarelli, M.,Jambrina, P.G.,Steiner, R.A.; Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold.; Chem Sci, 14:10547-10560, 2023; PubMed: 37799987; DOI: 10.1039/d3sc03044j

Experimental method

X-RAY DIFFRACTION (2.003 Å)