8OWP

Crystal structure of Mycobacterium smegmatis CoaB in complex with CTP and 2-(1-(4-hydroxyphenyl)-5-phenyl-1H-indol-3-yl)-2-oxoacetic acid

8OWP の概要

• エントリーDOI: 10.2210/pdb8owp/pdb
• 分子名称: Coenzyme A biosynthesis bifunctional protein CoaBC, CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: coab, coabc, fragment inhibitor, ligase
• 由来する生物種: Mycolicibacterium smegmatis MC2 155
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 102320.02

構造登録者

Mendes, V.,Blundell, T.L. (登録日: 2023-04-28, 公開日: 2024-05-08)

• 主引用文献: Hess, J.,Mendes, V.,Evans, J.C.,Trapero, A.,Marchetti, C.,Blaszczyk, M.,Bryant, O.,Spry, C.,Coyne, A.G.,Boshoff, H.I.M.,Barry, C.E.,Mizrahi, V.,Blundell, T.L.,Abell, C.; Development of new inhibitors against M. tuberculosis CoaBC using a fragment based approach.; To Be Published,

実験手法

X-RAY DIFFRACTION (1.993 Å)