8OQS
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-83
8OQS の概要
エントリーDOI | 10.2210/pdb8oqs/pdb |
分子名称 | 3-hydroxyacyl-CoA dehydrogenase, Putative acyltransferase Rv0859, SULFATE ION, ... (6 entities in total) |
機能のキーワード | fatty acid beta oxidation complex, mycobacterium tuberculosis, tfe, fragment screening, substrate channeling, oxidoreductase |
由来する生物種 | Mycobacterium tuberculosis H37Rv 詳細 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 246947.86 |
構造登録者 | |
主引用文献 | Dalwani, S.,Metz, A.,Huschmann, F.U.,Weiss, M.S.,Wierenga, R.K.,Venkatesan, R. Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them. Acta Crystallogr D Struct Biol, 80:605-619, 2024 Cited by PubMed: 39012716DOI: 10.1107/S2059798324006557 主引用文献が同じPDBエントリー |
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