8OPX
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Trehalose (Fragment-B-TRE)
8OPX の概要
エントリーDOI | 10.2210/pdb8opx/pdb |
関連するBIRD辞書のPRD_ID | PRD_900006 |
分子名称 | 3-hydroxyacyl-CoA dehydrogenase, Putative acyltransferase Rv0859, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ... (6 entities in total) |
機能のキーワード | fatty acid beta oxidation complex, mycobacterium tuberculosis, tfe, fragment screening, substrate channeling, oxidoreductase |
由来する生物種 | Mycobacterium tuberculosis H37Rv 詳細 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 243922.43 |
構造登録者 | |
主引用文献 | Dalwani, S.,Metz, A.,Huschmann, F.U.,Weiss, M.S.,Wierenga, R.K.,Venkatesan, R. Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024 Cited by DOI: 10.1101/2024.01.11.575214主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.9 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード