8OMF
Crystal structure of hKHK-C in complex with compound-4
Summary for 8OMF
| Entry DOI | 10.2210/pdb8omf/pdb |
| Descriptor | Ketohexokinase, SULFATE ION, compound, ... (4 entities in total) |
| Functional Keywords | ketohexokinase, khk, sugar kinase, species selectivity, isoform selectivity, inhibited, sugar binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 69510.67 |
| Authors | Ebenhoch, R.,Pautsch, A. (deposition date: 2023-03-31, release date: 2023-09-27, Last modification date: 2023-10-18) |
| Primary citation | Ebenhoch, R.,Bauer, M.,Romig, H.,Gottschling, D.,Kley, J.T.,Heine, N.,Weber, A.,Uphues, I.,Nar, H.,Pautsch, A. Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design. Acta Crystallogr D Struct Biol, 79:871-880, 2023 Cited by PubMed: 37712434DOI: 10.1107/S2059798323006137 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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