8OMF

Crystal structure of hKHK-C in complex with compound-4

8OMF の概要

• エントリーDOI: 10.2210/pdb8omf/pdb
• 分子名称: Ketohexokinase, SULFATE ION, compound, ... (4 entities in total)
• 機能のキーワード: ketohexokinase, khk, sugar kinase, species selectivity, isoform selectivity, inhibited, sugar binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69510.67

構造登録者

Ebenhoch, R.,Pautsch, A. (登録日: 2023-03-31, 公開日: 2023-09-27, 最終更新日: 2023-10-18)

• 主引用文献: Ebenhoch, R.,Bauer, M.,Romig, H.,Gottschling, D.,Kley, J.T.,Heine, N.,Weber, A.,Uphues, I.,Nar, H.,Pautsch, A.; Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design.; Acta Crystallogr D Struct Biol, 79:871-880, 2023; PubMed: 37712434; DOI: 10.1107/S2059798323006137

実験手法

X-RAY DIFFRACTION (2.14 Å)