8OK5

Variant Surface Glycoprotein VSG11 monomer with iodine

Summary for 8OK5

Entry DOI	10.2210/pdb8ok5/pdb
Descriptor	Variant surface glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-glucopyranose, ... (5 entities in total)
Functional Keywords	variant surface glycoprotein suramin trypanosomiasis drug resistance glycosylation, membrane protein
Biological source	Trypanosoma brucei brucei
Total number of polymer chains	1
Total formula weight	48160.04
Authors	Zeelen, J.P.,Stebbins, C.E.,Aresta-Branco, F. (deposition date: 2023-03-27, release date: 2023-09-13)
Primary citation	Dakovic, S.,Zeelen, J.P.,Gkeka, A.,Chandra, M.,van Straaten, M.,Foti, K.,Zhong, J.,Vlachou, E.P.,Aresta-Branco, F.,Verdi, J.P.,Papavasiliou, F.N.,Stebbins, C.E. A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17:e0011621-e0011621, 2023 Cited by PubMed: 37656766 DOI: 10.1371/journal.pntd.0011621 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.27 Å)

Structure validation