8OK5

Variant Surface Glycoprotein VSG11 monomer with iodine

8OK5 の概要

• エントリーDOI: 10.2210/pdb8ok5/pdb
• 分子名称: Variant surface glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: variant surface glycoprotein suramin trypanosomiasis drug resistance glycosylation, membrane protein
• 由来する生物種: Trypanosoma brucei brucei
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48160.04

構造登録者

Zeelen, J.P.,Stebbins, C.E.,Aresta-Branco, F. (登録日: 2023-03-27, 公開日: 2023-09-13)

• 主引用文献: Dakovic, S.,Zeelen, J.P.,Gkeka, A.,Chandra, M.,van Straaten, M.,Foti, K.,Zhong, J.,Vlachou, E.P.,Aresta-Branco, F.,Verdi, J.P.,Papavasiliou, F.N.,Stebbins, C.E.; A structural classification of the variant surface glycoproteins of the African trypanosomey.; Plos Negl Trop Dis, 17:e0011621-e0011621, 2023; PubMed: 37656766; DOI: 10.1371/journal.pntd.0011621

実験手法

X-RAY DIFFRACTION (1.27 Å)