8KGE

Dimeric tail tube protein gpVs of bacteriophage lambda

8KGE の概要

• エントリーDOI: 10.2210/pdb8kge/pdb
• EMDBエントリー: 35818 35824 35825 37218
• 分子名称: Tail tube protein (1 entity in total)
• 機能のキーワード: bacteriophage, caudovirales, siphoviridae, tail complex, delivery device, phage lambda, cryo-em, viral protein
• 由来する生物種: Escherichia phage lambda
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51663.56

構造登録者

Wang, J.W. (登録日: 2023-08-18, 公開日: 2023-10-18, 最終更新日: 2025-07-16)

主引用文献

Wang, C.,Duan, J.,Gu, Z.,Ge, X.,Zeng, J.,Wang, J.
Architecture of the bacteriophage lambda tail.
Structure, 32:35-, 2024

PubMed Abstract: Bacteriophage lambda has a double-stranded DNA genome and a long, flexible, non-contractile tail encoded by a contiguous block of 11 genes downstream of the head genes. The tail allows host recognition and delivery of viral DNA from the head shell to the cytoplasm of the infected cell. Here, we present a high-resolution structure of the tail complex of bacteriophage lambda determined by cryoelectron microscopy. Most component proteins of the lambda tail were determined at the atomic scale. The structure sheds light on the molecular organization of the extensively studied tail of bacteriophage lambda.

PubMed: 37918400
DOI: 10.1016/j.str.2023.10.006

実験手法

ELECTRON MICROSCOPY (3.8 Å)