8KB6

Crystal Structure of Canine TNF-alpha

Summary for 8KB6

• Entry DOI: 10.2210/pdb8kb6/pdb
• Descriptor: Tumor necrosis factor (2 entities in total)
• Functional Keywords: immune system, inflammatory, cytokine
• Biological source: Canis lupus familiaris (dog)
• Total number of polymer chains: 1
• Total formula weight: 16789.99

Authors

Lee, C.C.,Wang, A.H.-J. (deposition date: 2023-08-03, release date: 2024-05-22)

• Primary citation: Lee, C.C.,Kuo, W.C.,Chang, Y.W.,Hsu, S.F.,Wu, C.H.,Chen, Y.W.,Chang, J.J.,Wang, A.H.; Structure-based development of a canine TNF-alpha-specific antibody using adalimumab as a template.; Protein Sci., 33:e4873-e4873, 2024; PubMed: 38111376; DOI: 10.1002/pro.4873

Experimental method

X-RAY DIFFRACTION (1.85016596237 Å)