8K82

Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA

This is a non-PDB format compatible entry.

Summary for 8K82

• Entry DOI: 10.2210/pdb8k82/pdb
• EMDB information: 36945
• Descriptor: 18S rRNA, Small ribosomal subunit protein uS3, 40S ribosomal protein S4-A, ... (88 entities in total)
• Functional Keywords: 80s ribosome, tigecycline, antibiotic, ribosome
• Biological source: Saccharomyces cerevisiae; More
• Total number of polymer chains: 85
• Total formula weight: 3288578.86

Authors

Buschauer, R.,Beckmann, R.,Cheng, J. (deposition date: 2023-07-28, release date: 2024-07-10)

• Primary citation: Li, X.,Wang, M.,Denk, T.,Buschauer, R.,Li, Y.,Beckmann, R.,Cheng, J.; Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.; Nat Commun, 15:5481-5481, 2024; PubMed: 38942792; DOI: 10.1038/s41467-024-49797-7

Experimental method

ELECTRON MICROSCOPY (3 Å)