8K79
Crystal structure of c-SRC kinase domain bound by TPX-0022
Summary for 8K79
Entry DOI | 10.2210/pdb8k79/pdb |
Descriptor | Proto-oncogene tyrosine-protein kinase Src, Elzovantinib (3 entities in total) |
Functional Keywords | src, tpx-0022, transferase |
Biological source | Gallus gallus (chicken) |
Total number of polymer chains | 2 |
Total formula weight | 66272.12 |
Authors | |
Primary citation | Qu, L.,Lin, H.,Dai, S.,Guo, M.,Chen, X.,Jiang, L.,Zhang, H.,Li, M.,Liang, X.,Chen, Z.,Wei, H.,Chen, Y. Structural insight into the macrocyclic inhibitor TPX-0022 of c-Met and c-Src. Comput Struct Biotechnol J, 21:5712-5718, 2023 Cited by PubMed: 38074469DOI: 10.1016/j.csbj.2023.11.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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