8K4C
Crystal structure of PDE4D complexed with ethaverine hydrochloride
Summary for 8K4C
Entry DOI | 10.2210/pdb8k4c/pdb |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4D, 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | pde4d, complex, ethaverine hydrochloride, inhibitor, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 81225.19 |
Authors | |
Primary citation | Liu, J.,Zhang, X.,Chen, G.,Shao, Q.,Zou, Y.,Li, Z.,Su, H.,Li, M.,Xu, Y. Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors. Eur.J.Med.Chem., 262:115893-115893, 2023 Cited by PubMed: 37918035DOI: 10.1016/j.ejmech.2023.115893 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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