8K3K

The crystal structure of nanobody Nb4 in complex with receptor binding domain (RBD) of BA.1 Spike protein

8K3K の概要

• エントリーDOI: 10.2210/pdb8k3k/pdb
• 分子名称: Spike protein S1, Nanobody Nb4 (3 entities in total)
• 機能のキーワード: nanobody, receptor binding domain, sars-cov-2, complex, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 45387.51

構造登録者

Wang, H.Y.,Xu, W.Q. (登録日: 2023-07-16, 公開日: 2024-01-24)

• 主引用文献: Yao, H.,Wang, H.,Zhang, Z.,Lu, Y.,Zhang, Z.,Zhang, Y.,Xiong, X.,Wang, Y.,Wang, Z.,Yang, H.,Zhao, J.,Xu, W.; A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.; MedComm (2020), 4:e397-e397, 2023; PubMed: 37901798; DOI: 10.1002/mco2.397

実験手法

X-RAY DIFFRACTION (2.43 Å)