8K2D

Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A

This is a non-PDB format compatible entry.

Summary for 8K2D

• Entry DOI: 10.2210/pdb8k2d/pdb
• EMDB information: 36839
• Descriptor: 18S rRNA, Small ribosomal subunit protein uS7, 40S ribosomal protein S6-A, ... (88 entities in total)
• Functional Keywords: 80s ribosome, tigecycline, antibiotic, ribosome
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 84
• Total formula weight: 3327244.98

Authors

Buschauer, R.,Beckmann, R.,Cheng, J. (deposition date: 2023-07-12, release date: 2024-07-10)

• Primary citation: Li, X.,Wang, M.,Denk, T.,Buschauer, R.,Li, Y.,Beckmann, R.,Cheng, J.; Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.; Nat Commun, 15:5481-5481, 2024; PubMed: 38942792; DOI: 10.1038/s41467-024-49797-7

Experimental method

ELECTRON MICROSCOPY (3.2 Å)