8K0C

Cryo-EM structure of conformation 1 of complex of Nipah virus attachment glycoprotein G with 1E5 neutralizing antibody

Summary for 8K0C

Entry DOI	10.2210/pdb8k0c/pdb
EMDB information	36760
Descriptor	Heavy chain of 1E5 Fab fragments, Light chain of 1E5 Fab fragments, Glycoprotein G, ... (4 entities in total)
Functional Keywords	henipavirus, attachment glycoprotein tetramer complex, neutralizing antibody, dynamic structures, viral protein
Biological source	Macaca mulatta More
Total number of polymer chains	8
Total formula weight	223101.23
Authors	Sun, M.M. (deposition date: 2023-07-08, release date: 2024-05-01, Last modification date: 2024-06-05)
Primary citation	Fan, P.,Sun, M.,Zhang, X.,Zhang, H.,Liu, Y.,Yao, Y.,Li, M.,Fang, T.,Sun, B.,Chen, Z.,Chi, X.,Chen, L.,Peng, C.,Chen, Z.,Zhang, G.,Ren, Y.,Liu, Z.,Li, Y.,Li, J.,Li, E.,Guan, W.,Li, S.,Gong, R.,Zhang, K.,Yu, C.,Chiu, S. A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15:4330-4330, 2024 Cited by PubMed: 38773072 DOI: 10.1038/s41467-024-48601-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.18 Å)

Structure validation