8JXW
VUF6884-bound H4R/Gi complex
Summary for 8JXW
Entry DOI | 10.2210/pdb8jxw/pdb |
EMDB information | 36715 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr-g-protein complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 157339.56 |
Authors | |
Primary citation | Xia, R.,Shi, S.,Xu, Z.,Vischer, H.F.,Windhorst, A.D.,Qian, Y.,Duan, Y.,Liang, J.,Chen, K.,Zhang, A.,Guo, C.,Leurs, R.,He, Y. Structural basis of ligand recognition and design of antihistamines targeting histamine H 4 receptor. Nat Commun, 15:2493-2493, 2024 Cited by PubMed: 38509098DOI: 10.1038/s41467-024-46840-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.01 Å) |
Structure validation
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