8JWG

Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 without H1 helix in complex with MFQ

Summary for 8JWG

Entry DOI	10.2210/pdb8jwg/pdb
EMDB information	36674 36679 36681 36682
Descriptor	Multidrug resistance protein 1, Mefloquine (2 entities in total)
Functional Keywords	plasmodium falciparum, multidrug resistance protein 1, abc transporter, mfq complex, transport protein
Biological source	Plasmodium falciparum (isolate 3D7)
Total number of polymer chains	1
Total formula weight	163143.12
Authors	Li, M.,Si, K. (deposition date: 2023-06-29, release date: 2023-08-30)
Primary citation	Si, K.,He, X.,Chen, L.,Zhang, A.,Guo, C.,Li, M. The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain. Proc.Natl.Acad.Sci.USA, 120:e2219905120-e2219905120, 2023 Cited by PubMed: 37527341 DOI: 10.1073/pnas.2219905120 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.54 Å)

Structure validation